Antiphospholipid syndrome occurs when r immune system mistakenly attacks some of the normal proteins in r blood. Antiphospholipid syndrome can cause blood clots to form within arteries or veins. Antiphospholipid syndrome may cause blood clots to form in leg veins, a condition known as deep vein thrombosis (DVT).
The Euro-Phospholipid Group analyzed the prevalence of the most relevant clinical and immunological features in a cohort of 1000 APS npatients derived from 13 countries. A recent large multicenter study showed that β 2GPI-dependent aPL can be found in almost 10% of ng premenopausal women hospitalized for the first MI.
It's possible to have the antibodies associated with antiphospholipid syndrome without ever developing signs or symptoms. However, if have these antibodies, risk of developing blood clots increases particularly if : Become pregnant, Remain immobile for a period of time (such as when on bed rest or sitting during a long airline flight), Have surgery, Smoke cigarettes, Take oral contraceptives, Have high cholesterol and triglycerides levels.