Ciguatera fish poisoning (CFP) is a foodborne illness affecting humans worldwide. Humans acquire this illness by eating reef fish containing the naturally occurring toxins, ciguatoxins. Multiple ciguatoxins have been identified. CTX is derived from benthic dinoflagellates of the genus Gambierdiscus, growing predominantly in association with macroalgae in coral reefs in tropical and subtropical climates.
Treatment if performed within 3-4 hours of toxin ingestion, gastric decontamination with activated charcoal may help. Avoid administering ipecac syrup because of its potential to worsen fluid losses. Anti-emetics may control nausea and vomiting. Cool showers and antihistamines help relieve pruritus. Mannitol infusion can help alleviate neurologic symptoms.