Marburg virus disease (MVD) is human disease caused by any of the two marburgviruses Marburg virus (MARV) and Ravn virus (RAVV). In 1975, an Australian tourist became infected with MARV in Rhodesia.
There is currently no effective marburgvirus-specific therapy for MVD. Treatment is primarily supportive in nature and includes minimizing invasive procedures, balancing fluids and electrolytes to counterdehydration, administration of anticoagulants early in infection to prevent or control disseminated intravascular coagulation, administration of procoagulants late in infection to control hemorrhaging, maintaining oxygen levels, pain management, and administration of antibiotics or antimycotics to treat secondary infections
Marburg virus is related to viruses that cause hemorrhagic fevers — illnesses marked by severe bleeding (hemorrhage), organ failure and, in many cases, death. Over time, symptoms become increasingly severe and may include: Nausea and vomiting Diarrhea (may be bloody) Red eyes Raised rash Chest pain and cough Stomach pain Severe weight loss Bleeding, usually from the eyes, and bruising (people near death may bleed from other orifices, such as ears, nose and rectum) Internal bleeding..
Marburg virus live in animal hosts, and humans can contract the viruses from infected animals. After the initial transmission, the viruses can spread from person to person through contact with body fluids or contaminated needles.