Non-Hodgkin lymphoma, is a cancer that starts in cells called lymphocytes, which are part of the body's immune system. Lymphocytes are in the lymph nodes and other lymphoid tissues. Lymphomas are types of cancer derived from lymphocytes, a type of white blood cell.Non-Hodgkin's lymphoma is cancer that originates in your lymphatic system, the disease-fighting network spread throughout your body. Israel ranks first in Non-Hodgkin's Lymphoma (NHL) morbidity in the top 20 countries with the highest morbidity rates in the world, and second in mortality rates. In 2012, 1,304 new patients were diagnosed with NHL in Israel, 690 men and 614 women. The five-year survival rates are on the increase, and stand at an estimated 70%. This apparently involved enhanced treatment modalities.
Many new chemotherapy drugs are being studied in clinical trials. In recent years, these studies have led to the approval of drugs such as bendamustine (Treanda) and pralatrexate for use against certain types of lymphoma. Other studies are looking at new ways to combine drugs using different doses or different sequences of drugs. The following imaging studies should be obtained in a patient suspected of having NHL:
• Chest radiography
• Upper GI series with small bowel follow-through: In patients with head and neck involvement and those with a GI primary lesion
• CT scanning of the neck, chest, abdomen, and pelvis
• Bone scanning: Only in patients with bone pain, elevated alkaline phosphatase, or both
• Testicular ultrasonography: For opposite testis in male patients with a testicular primary lesion