Toxoplasmosis (tok-so-plaz-MOE-sis) is a disease that results from infection with the Toxoplasma gondii parasite, one of the world's most common parasites. Toxoplasmosis may cause flu-like symptoms in some people, but most people affected never develop signs and symptoms.Toxoplasma gondii (T. gondii) is a single-celled parasitic organism that can infect most animals and birds. Because it reproduces only in cats, wild and domestic felines are the parasite's ultimate host.When a person becomes infected with T. gondii,the parasite forms cysts that can affect almost any part of the body — often your brain and muscles, including the heart.
Pyrimethamine (Daraprim). This medication, typically used for malaria, is a folic acid antagonist. It may prevent your body from absorbing the B vitamin folate (folic acid, vitamin B-9), especially when you take high doses over a long period. For that reason, your doctor may recommend taking additional folic acid.Other potential side effects of pyrimethamine include bone marrow suppression and liver toxicity. Sulfadiazine. This antibiotic is used with pyrimethamine to treat toxoplasmosis.In the Israel, about 1,367,428 cases of Toxoplasmosis infection are reported in humans each year. Almost 10% of the Israel population is infected with Toxoplasmosis, a parasite of dogs and cats that can be passed from animals to humans.