Deep vein thrombosis, or deep venous thrombosis, (DVT) is the formation of a blood clot (thrombus) within a deep vein, predominantly in the legs. Non-specific signs may include pain, swelling, redness, warmness, and engorged superficial veins. DVT often develops in the calf veins and "grows" in the direction of venous flow, towards the heart. When DVT does not grow; it can be cleared naturally and dissolved into the blood (fibrinolysis).
Out of the total 714 Italian centers, a random sample of 214 were contacted and asked to take part in this study; of these, 146 replied (20.4% of total and 68.2% of the sample): 48 departments of general surgery, 46 departments of gynecology, and 52 departments of orthopedics. About 70% of the centers has appropriate information about surgery as a risk factor for VTE. The answers have provided evidence of an adequate knowledge of the instrumental and laboratory diagnostic pathways, useful to confirm the diagnosis of TE (80%).
The basic treatments for the disease are Anticoagulation, which prevents further coagulation, home treatment, stockings, walking, and repeat imaging and IVC filters, thrombolysis, and thrombectomy. The aims of the physicians are to prevent clot becoming larger, clot becoming lose and traveling to lungs, new clot formation and Post thrombotic syndrome.
Major Research on Disease
The current major research on the diseases are efficacy of low doses of heparin for the prevention of the DVT after a major surgery, accuracy of the clinical assessment for DVT, Decreased plasma levels of activated factor VII in patients with deep vein thrombosis etc.