Endometrial cancer is a type of cancer that begins in the uterus. The uterus is the hollow, pear-shaped pelvic organ in women where fetal development occurs. Endometrial cancer begins in the layer of cells that form the lining (endometrium) of the uterus.
Symptoms: Signs and symptoms of endometrial cancer may include: Vaginal bleeding after menopause. Bleeding between periods. An abnormal, watery or blood-tinged discharge from your vagina. Pelvic pain. Pain during intercourse.
Diagnosis: Endometrial cancer can be diagnosed by pelvic examination,transvaginal ultrasound,computed tomography,Magnetic resonance imaging,Endometrial biopsy, Dilatation and curetage.
Treament: Surgery (radical hysterectomy and bilateral salpingo-oophorectomy). Surgery followed by adjuvant chemotherapy with or without radiation therapy in stage II endometrial cancer that is likely to recur.
Epidemology: Rates vary worldwide and are highest in white women in Western populations. Some risk factors are related to reproduction, such as early age at menarche, late age at menopause and nulliparity.T he relationship between tamoxifen and endometrial cancer is not established. Obesity, diabetes and hypertension increase the risk of endometrial cancer while smoking, low-fat diets and physical exercise appear to decrease the risk; all of these possibly exert their effects by various indirect influences on oestrogen levels, thus influencing the level of stimulation of the target endometrial epithelium.