The Epstein Barr virus (EBV), also called human herpesvirus 4 (HHV-4), is one of eight viruses in the herpes family, and is one of the most common viruses in humans. It is best known as the cause of infectious mononucleosis.
Symptoms: The manifestations of primary EBV infection include: Infectious mononucleosis (IM): This is the most common medical condition associated with EBV. IM is characterized by extreme fatigue, tonsillitis and/or inflamed throat (pharyngitis), enlarged, tender lymph nodes in the neck, and moderate to high fever.
Diagnosis: Fever, fatigue, and sore throat could also be signs of other illnesses, like the flu or a cold. He might find signs that you have mono, such as an enlarged spleen, an organ in your belly that filters blood.And have a swollen liver and white patches on your tonsils.
Treament: There is no specific treatment for infectious mononucleosis, other than treating the symptoms. In severe cases, steroids such as Corticosteroids may be used to control the swelling of the throat and tonsils. The illness should be investigated further to determine if it meets the criteria for chronic fatigue syndrome, or CFS. This process includes ruling out other causes of chronic illness or fatigue.
Epidemology: Epstein-Barr virus (EBV) specific antigens were determined in 3732 healthy babies and children aged 0-10 years living in the Bari area (South Italy). IgG antibodies against EBV capsid antigen (VCA) were found in 2713 subjects (72.7%). After 2 years the frequency of positive children rose progressively reaching steady levels between 5 and 7 years (80.2%) and between 8 and 10 years (81.9%). IgA antibodies against VCA, IgG anti-early viral antigen (EA) and IgG against virus-associated nuclear antigens (EBNA) were found in 17.9%, 15.9% and 25.7% of the subjects tested, respectively.