Lipomas are the most common soft-tissue tumor. These slow-growing, benign fatty tumors form soft, lobulated masses enclosed by a thin, fibrous capsule. Lipomas are common benign mesenchymal tumors. They may develop in virtually all organs throughout the body. The anatomy depends on the tumor site. Subcutaneous lipomas are usually not fixed to the underlying fascia. The fibrous capsule must be removed to prevent recurrence. The cause of lipomas is not completely understood, but the tendency to develop them is inherited.
In a cross-sectional analysis in 582 lipodystrophic patients with HIV, the prevalence of suprapubic lipomas was 9.4%, but these lipomas were more common in patients with dorsocervical fat deposition (18.5%), suggesting a common pathogenesis between these two entities. Other risk factors for pubic lipomas were female gender, obesity (body mass index ≥ 30) and shorter duration of HIV infection.