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Nasopharyngeal Carcinoma
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Nasopharyngeal carcinoma is a rare type of head and neck cancer. It starts in the upper part of your throat, behind the nose. This area is called the nasopharynx. The nasopharynx is precariously placed at the base of your skull, above the roof of your mouth. The malignancy of nasopharyngeal cancer has an intermediate incidence of five to nine cases per 100,000 population per year in inhabitants of Italy. Radiation therapy is the mainstay of treatment, with chemotherapy used in advanced cases.
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Concurrent cisplatin, 5-fluorouracil, and radiotherapy have been shown to improve survival. Approaches to primary prevention of NPC remain under consideration.Thus, there is a need to conduct secondary prevention, such as improving rates of early detection, early diagnosis, and early treatment in NPC patients. Achievements in these areas might bring hope of providing a successful screening model in cancer.
Expert PPTs
- Jun Yang
Histopathology and pathogenesis of digestive system and Female genital and breast tumors
PPT Version | PDF Version - Aruna Turaka
Intensity modulated radiation therapy
PPT Version | PDF Version
Speaker PPTs
- Werner Boecker
Syringomatous tumour of the nipple and low-grade adenosquamous carcinoma: Evidence for a common origin
PPT Version | PDF Version - Tibor Tot
Multiparameter characterization of breast carcinoma: subgross, microscopy, proteins, and genes
PPT Version | PDF Version - Fathia El Sharkawi
The effect of PTEN and TRAIL genes loaded on nanoparticles on hepatocellular carcinoma
PPT Version | PDF Version - Yosef Yarden
Classically, the 3âuntranslated region (3âUTR) is that region in eukaryotic protein-coding genes from the translation termination codon to the polyA signal. It is transcribed as an integral part of the mRNA encoded by the gene. However, there exists another kind of RNA, which consists of the 3âUTR alone, without all other elements in mRNA such as 5âUTR and coding region. The importance of independent 3âUTR RNA (referred as I3âUTR) was prompted by results of artificially introducing such RNA species into malignant mammalian cells. Since 1991, we found that the middle part of the 3âUTR of the human nuclear factor for interleukin-6 (NF-IL6) or C/EBP gene exerted tumor suppression effect in vivo. Our subsequent studies showed that transfection of C/EBP 3âUTR led to down-regulation of several genes favorable for malignancy and to up-regulation of some genes favorable for phenotypic reversion. Also, it was shown that the sequences near the termini of the C/EBP 3âUTR were important for its tumor suppression activity. Then, the C/EBP 3âUTR was found to directly inhibit the phosphorylation activity of protein kinase CPKC in SMMC-7721, a hepatocarcinoma cell line. Recently, an AU-rich region in the C/EBP 3âUTR was found also to be responsible for its tumor suppression. Recently we have also found evidence that the independent C/EBP 3âUTR RNA is actually exists in human tissues, such as fetal liver and heart, pregnant uterus, senescent fibroblasts etc. Through 1990âs to 2000âs, world scientists found several 3âUTR RNAs that functioned as artificial independent RNAs in cancer cells and resulted in tumor suppression. Interestingly, majority of genes for these RNAs have promoter-like structures in their 3âUTR regions, although the existence of their transcribed products as independent 3âUTR RNAs is still to be confirmed. Our studies indicate that the independent 3âUTR RNA is a novel non-coding RNA species whose function should be the regulation not of the expression of their original mRNA, but of some essential life activities of the cell as a whole.
PPT Version | PDF Version - Devathri Nanayakkara
Context specific role of deubiquitylase enzyme, USP9X in oral squamous cell carcinoma
PPT Version | PDF Version - Giselle L Gotamco
PDF Version - Igor Malyshev
GENETIC FEATURES OF NO GENERATING SYSTEMS AND RESISTANT TO EHRLICH ASCITES CARCINOMA
PPT Version | PDF Version - Lubna Mushtaque Vohra
Metaplastic carcinoma of the breast and p16 positivity: What does it mean?
PPT Version | PDF Version - Rubens Mendes Canuto de Oliveira
Progressive Form Of Biliary And Hepatic Paracoccidioidomycosis, Simulating Cholangiocarcinoma
PPT Version | PDF Version - Myron R Szewczuk
Transcriptional factor Snail and MMP-9 signaling axis controls tumor neovascularization, growth and metastasis in mouse model of human ovarian carcinoma
PPT Version | PDF Version - Mingsong Wu
Identification of differentially expressed genes in human lung adenocarcinoma: ERGIC3 as a novel lung cancer-related gene
PPT Version | PDF Version - Flavia Secco Tavares de Souza
A Comparative Study Among Elective Conventional Surgery, Urgency/Emergency Conventional Approaching and Elective Videolaparoscopic Surgery on the Treatment of Hospitalized Patients at First Surgeric Clinic of Federal Hospital of Bonsucesso with a Diagnostic of Colorectal adenocarcinoma, between January 2010 and December 2012
PPT Version | PDF Version - Ahmed G. Hegazi
Influence of honey in mice bearing Ehrlich carcinoma on immune status
PPT Version | PDF Version - Jian Jun Wei
MicroRNAs and the target genes in early tumorigenesis of fallopian/ovarian carcinoma
PPT Version | PDF Version
