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New born jaundice | Italy| PDF | PPT| Case Reports | Symptoms | Treatment

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New Born Jaundice

  • New born jaundice

    Neonatal physiologic jaundice results from simultaneous occurrence of the following two phenomena : • Bilirubin production is elevated because of increased breakdown of fetal erythrocytes. This is the result of the shortened lifespan of fetal erythrocytes and the higher erythrocyte mass in neonates.Breastfeeding rates following the discharge of infants diagnosed with jaundice were not significantly different from those reported for the general population.

  • New born jaundice

    Hepatic excretory capacity is low both because of low concentrations of the binding protein ligandin in the hepatocytes and because of low activity of glucuronyl transferase, the enzyme responsible for binding bilirubin to glucuronic acid, thus making bilirubin water soluble (conjugation). Our year-long nursery sample examined otherwise healthy-appearing term infants for the prevalence of hyperbilirubinemia (defined as bilirubin levels exceeding 6 mg/dL [11mol/L]).

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