A passing episode of short-term memory loss without other signs or symptoms of neurological impairment. In transient global amnesia (TGA) the individual does not lose consciousness but does lose the ability to form new lasting memories. Motor function is not affected. The individual may be disoriented to place and time, may recognize that something is wrong, and may become distressed at this realization.
Brain MRI and/or CT scan Any patient presenting with features of transient global amnesia should receive an imaging test to rule out a stroke possibility, especially if significant risk factors are present. MRI with DWI can readily demonstrate acute ischemic changes early and guide management. In one study, higher resolution DWI imaging increased detection of hippocampal lesions in 27 patients with transient global amnesia, from 11 with standard resolution MRI to 22 with high resolution MRI.