Acute myeloid leukemia (AML), also known as acute myelogenous leukemia, acute myeloblastic leukemia, acute granulocytic leukemia or acute nonlymphocytic leukemia, is a fast-growing form of cancer of the blood and bone marrow. A morphological review system of the Japan Adult Leukemia Study Group has developed from the AML-87 through the AML-92 experience, reviewed 1427 (90%) of 1592 cases enrolled in the AML-87, -89, or -92 protocols for morphology; 1408 (88%) were eligible. The rate of diagnostic concordance between each institute and the Committee on Morphological Diagnosis ranged from 76% to 80%.
Symptoms; Many people often do not experience symptoms in the early stages of certain types of leukemia, or the symptoms develop slowly. Acute myeloid leukemia (AML) and acute lymphocytic leukemia (ALL) progress much faster and symptoms may worsen more quickly than with the chronic leukemias (CML and CLL).Some leukemia symptoms, like night sweats, fever, fatigue and achiness, often resemble flu-like symptoms. If you have the flu, symptoms will likely subside as you get better. Make an appointment to see your doctor if the symptoms persist longer than expected.
Therapeutic aspects; leukemia experts use state-of-the-art diagnostic tools, including advanced imaging and laboratory tests, to evaluate leukemia. This diagnostic evaluation takes about three to five days. In AML, the bone marrow may also make abnormal red blood cells and platelets. The number of these abnormal cells increases rapidly, and the abnormal (leukemia) cells begin to crowd out the normal white blood cells, red blood cells and platelets that the body needs.