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Amniotic fluid embolism (AFE) is a rare obstetric emergency in which amniotic fluid, fetal cells, hair, or other debris enters the mother's blood stream via the placental bed of the uterus and trigger an allergic reaction. This reaction then results in cardiorespiratory (heart and lung) collapse and coagulopathy. Amniotic fluid embolism (AFE) is a pregnancy complication that causes life-threatening conditions, such as heart failure. It can affect you, your baby, or both of you.
There is no particular treatment for amniotic liquid embolism, and introductory crisis administration is the same concerning some other reason for sudden maternal breakdown - with cardiovascular and respiratory revival and adjustment of the coagulopathy. Be that as it may, more up to date research with creature models recommend that critical embolism of any material is trailed by platelet degranulation, pneumonic hypertension because of serotonin and thromboxane, and systemic hypotension because of vagal incitement.Biochemical mediators found in the amniotic fluid are thought to trigger the main features of anaphylactic reaction with multisystem involvement. The fetal products found in suspension in the amniotic fluid are responsible only for the minor effects caused by the actual mechanical obstruction.
The rate of AFE has been accounted for to extend from 1 in 8000 to 1 in 80,000 deliveries. The disorder ordinarily happens amid work, not long after vaginal or cesarean conveyance, or amid second-trimester widening and clearing strategies. In the national registry, 70% of the cases happened amid work, 19% were recorded amid cesarean conveyance, and 11% happened after vaginal delivery. All of the cases noted amid cesarean area had their onset not long after conveyance of the newborn child.The overall maternal mortality rate in India during 2007- 2009 was 102 per 100,000 live births1 . 41-90% of maternal deaths in this country are caused by direct obstetric causes viz. haemorrhage, infection, and hypertensive disorders, ruptured uterus, hepatitis, and anemia.