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Definition: Any type of depression can make you feel sad and keep you from enjoying life. However, atypical depression — also called depression with atypical features — means that your depressed mood can brighten in response to positive events. Other key symptoms include increased appetite, sleeping too much, feeling that your arms or legs are heavy, and feeling rejected.
Symptoms: Depression that temporarily lifts in response to good news or positive events, Increased appetite that can cause weight gain, Increased desire to sleep, usually more than 10 hours a day, Heavy, leaden feeling in your arms or legs that lasts an hour or more in a day — a feeling that is different from fatigue, Sensitivity to rejection or criticism, which affects your relationships, social life or job.
Statistics: In total, 141 (14.0%) participants were diagnosed with MetS and 57 (5.6%) were diagnosed with MDD (14 had atypical and 43 had non-atypicalMDD). The prevalence of MetS was the highest in the group with atypical depression, followed by the non-atypical depression and no MDD groups, respectively, with a marginally significant trend (P = 0.07). The adjusted odds ratios of MetS associated with depression were 3.8 (95% confidence interval [CI] 1.1-13.2) for atypical depression and 1.6 (95% CI 0.7-3.6) for non-atypical depression. Among the five features of atypical depression, only hyperphagia was significantly related to MetS (odds ratio 2.7, 95% CI 1.8-4.1).