Coronary artery disease (CAD) is the most Common type of heart disease, also referred to as coronary heart disorder. Coronary arteries are the essential blood vessels that supply your heart with blood, oxygen and nutrients. CAD occurs when these that provide blood to coronary heart muscle turn out to be hardened and narrowed. Atherosclerosis (regularly known as “hardening” or “clogging” of the arteries) is the buildup of cholesterol and fatty deposits (referred to as plaques) on the internal walls of the arteries. These plaques can avert blood go with the flow to the center muscle by clogging the artery or via causing abnormal artery tone and function.
Trends in CHD mortality and coronary risk factors have not been uniform and may vary by sex, age, and region. In the 2 largest metropolitan areas, Tokyo and Osaka, where 17% of the total Japanese population resides, the CHD mortality decline was small for men 30 to 49 years of age compared with those residing in the rest of Japan.
Treatment for CAD involves lifestyle changes, if necessary, drugs and certain medical procedures. Various drugs that are used to treat CAD are Cholesterol-modifying medications, Beta blockers, Nitroglycerin, Angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs). Some of the Procedures to restore and improve blood flow like Angioplasty and stent placement (percutaneous coronary revascularization), Coronary artery bypass surgery.
Some of the Major researches on Coronary artery disease in Japan are Development of coronary artery lesions in indolent kawasaki disease following initial spontaneous defervescence: a retrospective cohort study, Investigation of MDA-LDL (malondialdehyde-modified low-density lipoprotein) as a prognostic marker for coronary artery disease in patients with type 2 diabetes mellitus.