Therapeutic medication involves intake of Acarbose and Somatostatin. Somatostatin and its synthetic analogue octreotide (Sandostatin) have been used with short-term success in patients with dumping syndrome, but the long-term efficacy of octreotide is much less favorable. They exert a strong inhibitory effect on the release of insulin and several gut-derived hormones. An estimated 25-50% of all patients who have undergone gastric surgery have some symptoms of dumping. However, only 1-5% are reported to have severe disabling symptoms. The incidence of significant dumping has been reported to be 6-14% in patients after truncal vagotomy and drainage and from 14-20% after partial gastrectomy. Bariatric surgery is the only satisfactory long-term treatment for severe obesity (body mass index [BMI] 40 kg/m� or greater, or 35 kg/m� or greater with severe obesity-associated comorbidities, such as diabetes, obstructive sleep apnea, or debilitating degenerative arthritis). Even in specialized units, the mortality rate of bariatric surgery may be 1%, and serious complications may occur in about 10% of cases. A female preponderance exists in the incidence of postgastrectomy syndromes.
Dumping syndrome is common after gastric surgery. It is a group of symptoms that may result from having part of your stomach removed or from other surgery involving the stomach. The symptoms range from mild to severe and often subside with time. Although you may find dumping syndrome alarming at first, it is not life threatening. You can control it by making changes in what and how you eat. By controlling dumping syndrome, you will also be avoiding the foods that tend to make you gain weight. Symptoms of this disease occurs in two phases: Early phase & late phase Most common symptoms include a feeling of fullness, even after eating just a small amount, Abdominal cramping or pain, Nausea or vomiting, Severe diarrhea, Sweating, flushing, Rapid heartbeat etc.
Maintaining balanced diet, avoiding disease causing foods, change of eating habits and medicines, etc. People who have gastric dumping syndrome need to eat several small meals a day that are low in carbohydrates, avoiding simple sugars, and should drink liquids between meals, not with them. Fiber delays gastric emptying and reduces insulin peaks. People with severe cases take medicine (such as octreotide and cholestyramine) or proton pump inhibitors (such as pantoprazole and omeprazole) to slow their digestion. Doctors may also recommend surgery. Surgical intervention may include conversion of a Billroth I to a Roux-en Y gastrojejunostomy.