The most common type of lip cancer begins in the squamous cells, the thin, flat cells that line the lips and mouth. Lip cancer symptoms are very similar to those of other types of oral cancer. It can often be mistaken for a cold that won’t go away, or a persistent toothache. Other symptoms and signs include, A sore in the mouth that does not heal, Persistent mouth pain, A lump or thickening in the cheek, A white or red patch on the gums, tongue, tonsil, or lining of the mouth, A sore throat or feeling that something is caught in the throat that does not go away.
A combination of these therapies can be used. The age-standardized mortality rates among the males increased from 1.14 per 100,000 person--years in 1952 to 1.84 in 1991, whereas the corresponding rate among females changed little over the same period. Cancer of the tongue was the most common cause of death in Japan among the five studied oral regions: lip, tongue, floor of the mouth, major salivary glands and oropharynx, males aged under 54 born in 1920 or later were found to have an increased risk of such disease.