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Broadly defined, nasal polyps are abnormal lesions that originate from any portion of the nasal mucosa or paranasal sinuses. Conditions leading to chronic inflammation in the nasal cavity such as bronchial asthma can lead to nasal polyps. Presence of asthma, however, was an independent predictor for the existence of NP, which was observed in 57.6% of asthmatics vs. 25% of nonasthmatics (p = 0.0015).
A combined medical and surgical treatment is recommended for symptoms control in preventing symptomatic NP recurrence. Oral and topical nasal steroid administration is the primary medical therapy for nasal polyposis. There is an urgent need for randomized placebo controlled trials to study the effect of antibiotics in chronic rhinosinusitis and exacerbations of chronic rhinosinusitis.
