Sclerosing mesenteritis is part of a spectrum (including mesenteric lipodystrophy and mesenteric panniculitis) of idiopathic primary inflammatory and fibrotic processes that affect the mesentery. Pathophysiologically, these processes may affect the integrity of the gastrointestinal lumen and mesenteric vessels by a mass effect. Sclerosing mesenteritis occurs when the tissue mesentery that holds the small intestines in place becomes inflamed and forms scar tissue.Sclerosing mesenteritis can cause abdominal pain, bloating and diarrhea. In rare cases, scar tissue formed by sclerosing mesenteritis can block food from moving through your digestive tract. Surgery may be necessary in this situation.
Sclerosing mesenteritis is characterized by chronic inflammation, fibrosis and fat necrosis, and is thought to originate from the small bowel mesentery.Sclerosing mesenteritis is chronic inflammation and fibrosis of the mesentery of unknown etiology. sclerosing mesenteritis is asymptomatic, gastrointestinal symptoms such as abdominal pain, nausea/vomiting, bloating, loss of appetite, weight loss and diarrhea or constipation, Occasionally, intermittent partial bowel obstruction is encountered. Non-gastrointestinal symptoms include fatigue, weight loss, night sweats and fever.
The Sclerosing mesenteritis has statistical significance i.e. A 60-year-old female who had been ill with ulcerative colitis for more than ten years presented with upper abdominal pain. A flare-up of ulcerative colitis was unlikely, because she did not report rectal bleeding, altered bowel habit, and changes of stool form. A poorly defined mass with mild tenderness was palpable in the upper abdomen, with increased levels of serum pancreatic enzymes, leading us to suspect pancreatic disease.