Travelers' diarrhea is the most common travel-related infection. It may be caused by many different organisms, including bacteria. In addition to diarrhea, symptoms may include nausea, vomiting, abdominal pain, fever, sweats, chills, headache, and malaise. The chief complication is dehydration, which may become severe, especially in warmer climes. The estimated prevalence of people in China are affected with Travelers' diarrhea is 4,681,360 extrapolate the above incidence rate for Traveler's diarrhea to the populations.
The mainstay of treatment is fluid replacement and an antimotility drug such as loperamide 4 mg po initially, followed by 2 mg po for each subsequent episode of diarrhea qid in tablet or liquid form may reduce the Traveler's diarrhea. Helsinki University Hospital Laboratory developed a low-cost, high-throughput qPCR assay for use in routine diagnostic analysis and research. It detects the pathogenic bacteria most commonly associated with TD in stool samples with 100% sensitivity and specificity, compared with reference methods.