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Journal of Genetics and DNA Research is a reputed peer reviewed, open access journal that aims to publish research articles that explore the role of genetics to various human disorders and the way to address them effectively.
The journal thus aim at geneticists, DNA experts, counsellors, medical professionals, clinical and diagnostic practitioners, researchers and students that work on various evolutionary and developmental genetics.
It encompasses a broad spectrum of themes in the field of genetics , including Genetic Code; Genetic Disorder; Genetic linkages; Genome Biology; Genome Sequencing; Human Genetics; Mendelian Genetics; DNA Replication; Functional Genomics; Gene cloning; Genetic Probes; Genetically engineering foods; Recombinant DNA; Trans-Genesis; RNA Splicing; DNA fingerprinting; Chromosomal Abnormalities; Gene Flow; Genetic Diversity; Genetic Syndromes; Hereditary Diseases; Mutation; Inherited Diseases; Population Genetics, etc.
The journal encourages original manuscripts for publication in the form of research articles, reviews, commentaries, short communication, letters to the editors, editorials, etc.
The authors can submit the manuscript online at https://www.editorialmanager.com/openaccessjournals/default.aspx or send it as an e-mail attachment at [email protected]
A gene is a sequence of DNA or RNA that is needed to contribute to a function. They are the working subunits of DNA that contains a particular set of instructions, usually coding for a particular protein or for a particular function. They are the basic physical and functional units of heredity.
DNA mutations are permanent changes in the DNA sequence of a gene, such that the sequence differs from what is found in most people. Mutations range in size; they can affect anywhere from a single DNA base pair to a large segment of a chromosome that includes multiple genes. They change the way a cell or whole organism functions. Some mutations even cause lethality, while others have no effect.
Single nucleotide polymorphisms, abbreviated as SNPs, are the most common type of genetic variations among people. Each SNP represents a difference in a single DNA building block, called a nucleotide. It is a variation in a single nucleotide that occurs at a specific position in the genome, where each variation is present to some appreciable degree within a population. It occurrs when a single nucleotide adenine (A), thymine (T), cytosine (C), or guanine (G) in the genome (or other shared sequence) differs between members of a species or paired chromosomes in an individual. SNPs in humans can affect how humans develop diseases and respond to pathogens, chemicals, medication, vaccines, and other agents.
Chromosomal abberations are the alterations in the structure of individual chromosome which may occur spontaneously or by induction through mutagenic agents. Such changes may result in quantitative alteration of genes or rearrangement of genes through loss, gain or reallocation of chromosomal segments.
An inherited disease is caused by a change or mutation in an individual’s DNA. Since genes are passed from parent to child, any changes in the DNA within a gene are also passed. Families at risk for such inherited diseases should consult a certified genetic counsellor. It may be necessary to check each parent's DNA to learn about some genetic inheritance patterns. A careful family pedigree (chart of members of the family) and history may help determine risks for certain problems.
Recombinant DNA technology is the deliberate, controlled manipulation of the genes in an organism with the intent of making that organism better in some way. It includes a bunch of techniques that produce unlimited amounts of otherwise unavailable or scarce biological product by introducing DNA isolated from animals or plants into bacteria and then harvesting the product from a bacterial colony.
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