The maghemite magnetic nanoparticles may also be encapsulated with a fluorescent dye. These engineered fluorescent magnetic dualmodal nanoparticles have a great advantage due to the combination of the magnetic and fluorescence imaging into one nanostructured material. These nanoparticles, which also selectively marks AÎ²40and insulin amyloid fibrils, might enable the early detection of plaques using both MRI and fluorescence microscopy, and therefore, may be applied in in vivo AD diagnosis studies.
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Last date updated on July, 2014