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Ampullary Cancer

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  • Ampullary Cancer

    Ampullary (AM-poo-la-ree) cancer is a rare cancer that forms in an area of your digestive system called the ampulla of Vater. The ampulla of Vater is where your bile duct and pancreatic duct join and empty into your small intestine. Ampullary cancer forms near many other parts of the digestive system, such as the liver, pancreas and small intestine. When ampullary cancer grows, it may affect these other organs.Jaundice is the most common symptom of ampullary cancer. This is because the tumor in the ampulla of Vater blocks the bile duct.

  • Ampullary Cancer

    If your doctors determine that you have ampullary cancer, the standard approach is to remove the tumor from the ampulla of Vater with a procedure called pancreaticoduodenal resection, or Whipple procedure. This procedure involves the resection, or removal, of the tumor in the affected portion of the ampulla of Vater and the surrounding areas.This makes the procedure minimally invasive (there's not a lot of cutting and bleeding) and improves the chances of recovering from the surgery. However, the most common way to perform the Whipple procedure is with an open abdomen.

  • Ampullary Cancer

    In the Far East, Korea demonstrated highly significant increasing mortality trends for both sexes [men (4.8–7.8), p<0.001; women (2.5–4), p<0.01), while women in Japan showed an increasing trend that was significant (p<0.05). In France, a trend towards increasing mortality was observed among women (p<0.001). An upward mortality trend in women achieving significance was also seen in Malta, Bulgaria, Greece, and Germany (p<0.05). A decline in mortality was seen in both sexes only in Canada [men (7.5–6.4), women (5.9–5); p<0.01], while for men there was a downward trend noticeable in Ireland, Switzerland, Austria, the UK, and Poland [p<0.05].

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