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Atrioventricular Canal Defect

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  • Atrioventricular canal defect

     Atrioventricular canal defect is a combination of heart problems resulting in a defect in the center of the heart. The condition occurs when there's a hole between the heart's chambers and problems with the valves that regulate blood flow in the heart.  The condition is often associated with Down syndrome. Atrioventricular canal defect allows extra blood to flow to the lungs. Untreated, atrioventricular canal defect can cause heart failure and high blood pressure in the lungs.

  • Atrioventricular canal defect

    Of the 275 children with DS, 160 had congenital heart disease. The most frequent cardiopathies were interauricular septal defect (IASD), interventricular septal defect (IVSD) and patent ductus arteriousus (PDA) (90%). In contrast to the data from other countries, only 14 patients (8%) had atrioventricular septal defect (AVSD). Twenty-five patients died (15%) from sepsis and cardiogenic shock.

  • Atrioventricular canal defect

    Patients with incomplete atrioventricular septal defects (AVSDs) present with signs and symptoms similar to those of secundum atrial septal  defects (ASDs) and, as such, rarely require medical therapy. Medical therapy in patients with complete atrioventricular septal defects consists of aggressive anticongestive treatment for the signs and symptoms of congestive heart failure (CHF). The mainstays of medical therapy are furosemide (for diuresis for the volume-overloaded heart), digoxin (as a mild inotrope), and ACE inhibitors (for afterload reduction).

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