Intussusception is a serious disorder in which part of the intestine slides into an adjacent part of the intestine. This "telescoping" often blocks food or fluid from passing through. Intussusception also cuts off the blood supply to the part of the intestine that's affected. Intussusception can lead to a tear in the bowel (perforation), infection and death of bowel tissue. Intussusception is the most common cause of intestinal obstruction in children younger than 3.
RV1 was associated with a short-term risk of intussusception in approximately 1 of every 51,000 to 68,000 vaccinated infants. A temporal increase in the risk for intussusception was seen within 7 days of administration of the first vaccine dose. It is still uncertain whether rotavirus vaccination has any impact on the overall incidence of intussusception. This finding has to be put in perspective with the well-documented substantial benefits of rotavirus vaccination.RV1 was associated with a short-term risk of intussusception in approximately 1 of every 51,000 to 68,000 vaccinated infants. The absolute number of deaths and hospitalizations averted because of vaccination far exceeded the number of intussusception cases that may have been associated with vaccination.
An enema is the first step in treatment. In fact, an enema that is used to diagnose intussusception may also help to treat it. Pressure from the air or fluid may cause the intestine to correct itself. The result of an enema treatment might not last, so patients usually stay in the hospital overnight for observation. Surgery is another treatment option. Intussusception surgery involves either a large incision or a small incision and a camera. This is called laparoscopic surgery. The type of surgery depends on the location and severity of the obstruction. Intussusception surgery may include removal of the affected section of intestine.