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Nasal polyps (NP) are common benign degeneration of nasal sinus mucosa which are mostly associated with chronic inflammations due to allergy, infection, asthma and aspirin sensitivity. Statistically, nasal polyps are more common in patients with nonallergic asthma (13%) than with allergic asthma (5%), and only 0.5% of 3000 atopic individuals have nasal polyps. Corticosteroids are the treatment of choice, either topically or systemically.
Direct injection into the polyp is not approved by the US Food and Drug Administration (FDA) because of reports of unilateral vision loss in 3 patients after intranasal steroid injection with Kenalog.Patients presenting with chronic rhinitis with polyps are found to have oedema of the nasal mucosa, low T regulator cell activity and low levels of beta-tissue growth factor. The opposite picture is seen with patients who have chronic rhinitis without polyps.
