Nonulcer stomach pain is a common problem with signs and symptoms of indigestion that have no obvious cause. Nonulcer stomach pain is also called functional dyspepsia or nonulcer dyspepsia. The lifetime prevalence of non-ulcer dyspepsia to be 23% among males and 18% among females-the prevalence increased significantly with age in both sexes, as did reflux symptoms.
Treatment of the symptoms associated with disordered motility is generally with two main groups of drugs. Firstly drugs that reduce the amount of acid that the stomach produces. Antacids and sucralfate were found to be no better than placebo in a literature review. H2-RAs have been shown to have marked benefit in poor quality trials (30% relative risk reduction), but only a marginal benefit in good quality trials.