Odontogenic lesions are cysts or tumors that develop in your jawbone or the soft tissues in your mouth. Odontogenic lesions can vary greatly in size and severity. These lesions are usually noncancerous (benign), but they may behave aggressively at times. Treatment generally involves surgical care but may include medical therapy for certain types of lesions. A total of 349 odontogenic tumors are found in Mexico in these, 345 were benign (98.8%), and 4 (1.1%) were malignant (3 were primary intraosseous carcinomas and 1 was a malignant ameloblastoma). The most frequently occurring tumors were odontoma (34.6%), ameloblastoma (23.7%), myxoma (17.7%), adenomatoid odontogenic tumor (7.1%), and calcifying odontogenic cyst (6.8%).
Treatment options for odontogenic lesions vary, depending on the type of lesion and stage of growth. In some cases, medications may help, but odontogenic lesions usually require surgical removal. A pathologist examines the removed tissue during surgery and reports a diagnosis within a few minutes, so that the surgeon can act on this information immediately. Expression of the transcription factor PITX2 in ameloblastic carcinoma, Primordial odontogenic tumor: clinicopathological analysis of six cases of a previously undescribed entity.