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Ureteral Obstruction

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  • Ureteral Obstruction

     Pathophysiology

    Ureteral Obstruction is structural or functional hindrance of normal urine flow, sometimes leading to renal dysfunction (obstructive nephropathy). Ureteral obstruction can be classified as intraluminal or extraluminal. Intraluminal causes include kidney stones, blood clots and scarring; these conditions usually cause unilateral obstruction and Extraluminal causes include several conditions related to enlarged masses that place pressure on the ureter and create obstructions.

  • Ureteral Obstruction

     Disease statistics

    The number of maternal deaths as a result of obstructed labour and/or rupture of the uterus varies between 4% and 70% of all maternal deaths, amounting to a maternal mortality rate as high as 410/100,000 live births.

  • Ureteral Obstruction

     Disease treatment

    Stents or drains placed in the ureter or in a part of the kidney called the renal pelvis may provide short-term relief of symptoms. Long-term relief from obstructive uropathy requires surgery. A Foley catheter, placed through the urethra into the bladder, may also be helpful.

  • Ureteral Obstruction

     Major research

    99mTc-DTPA is one of the most widely used radiopharmaceuticals to assess renal function of patients with suspected urinary obstruction, with excretion predominantly by glomerular filtration. Renal scintigraphy was preferentially used because it is a noninvasive and quick exam, providing rapid dynamic imaging of the kidneys, including renal flow, function, and urinary outflow evaluation.

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