Low frequency (1Hz) repetitive transcranial magnetic simulation (TMS) is known to reduce motor corticospinal excitability. Low Frequency (1 Hz) repetitive transcranial magnetic stimulation (LFrTMS/ 1Hz rTMS) is a useful method to study brain-behavior relationships by modulating cortical excitability. In addition it is also used to influence learning and rehabilitation in patients with neurological disorders. Any studies have failed to show any modulation in corticospinal excitability with LFrTMS while in other studies, the reported decrease ranges in magnitude from 16% to 30% and in durations from 10 minutes to 1 hour. Importantly, the specific parameters of rTMS stimulation including frequency, intensity and duration can influence the nature of its effects on corticospinal excitability. For example, 1 Hz rTMS. Some studies measured MEP amplitude evoked with suprathreshold single pulse TMS, while others used input-output curves, stimulating across a range of intensity levels.
Last date updated on June, 2014