Experimental measure have been done on the response of pigs with and without tonsillectomy to oral vaccination with heat-inactivated M. bovis and challenge with a virulent M. bovis field strain. Mycobacterium bovis is the causative agent of bovine tuberculosis and is also responsible for some cases of tuberculosis in human beings. M. bovis can cause disease in both cattle and humans yet rarely transmits between immuno-competent human hosts, while M. tuberculosis is a pathogen of humans that does not withstand in animal populations. Mycobacterium bovis causes animal tuberculosis (TB) in pigs, cattle, other mammalian species and humans. The disease transmission is high form animal to humans. However, the pathogen M. tuberculosis has low chances of sustainability to stay in the animal population. The immunological and physiological changes have been observed in cattle infected with virulent M. bovis as well as M. tuberculosis.
Last date updated on June, 2014