Antiphospholipid syndrome occurs when r immune system mistakenly attacks some of the normal proteins in r blood. Antiphospholipid syndrome can cause blood clots to form within arteries or veins. Antiphospholipid syndrome may cause blood clots to form in leg veins, a condition known as deep vein thrombosis (DVT). The Euro-Phospholipid Group analyzed the prevalence of the most relevant clinical and immunological features in a cohort of 1000 APS npatients derived from 13 countries.
Symptoms: Signs and symptoms of antiphospholipid syndrome may include: Blood clots in r legs (deep vein thrombosis, or DVT) that may travel to r lungs (pulmonary embolism), Repeated miscarriages or stillbirths and other complications of pregnancy, such as premature delivery and high blood pressure during pregnancy (preeclampsia), Stroke, Blood clots in the arteries of arms or legs (peripheral arterial thrombosis)
Risk factors for developing symptoms: It's possible to have the antibodies associated with antiphospholipid syndrome without ever developing signs or symptoms. However, if have these antibodies, risk of developing blood clots increases particularly if : Become pregnant, Remain immobile for a period of time (such as when on bed rest or sitting during a long airline flight), Have surgery, Smoke cigarettes, Take oral contraceptives, Have high cholesterol and triglycerides levels.