Coronary Artery Disease

Pathophisiology
Coronary artery disease (CAD) is the most Common type of heart disease, also referred to as coronary heart disorder. Coronary arteries are the essential blood vessels that supply your heart with blood, oxygen and nutrients. CAD occurs when these that provide blood to coronary heart muscle turn out to be hardened and narrowed. Atherosclerosis (regularly known as “hardening” or “clogging” of the arteries) is the buildup of cholesterol and fatty deposits (referred to as plaques) on the internal walls of the arteries. These plaques can avert blood go with the flow to the center muscle by clogging the artery or via causing abnormal artery tone and function.
Statistics
According to the latest WHO data published in may 2014 Coronary Heart Disease Deaths in Netherlands reached 10,976 or 10.58% of total deaths. The age adjusted Death Rate is 34.53 per 100,000 of population ranks Netherlands 168 in the world.

Treatment
Treatment for CAD involves lifestyle changes, if necessary, drugs and certain medical procedures. Various drugs that are used to treat CAD are Cholesterol-modifying medications, Beta blockers, Nitroglycerin, Angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs). Some of the Procedures to restore and improve blood flow like Angioplasty and stent placement (percutaneous coronary revascularization), Coronary artery bypass surgery.
Major Research
Some of the Major researches on Coronary artery disease in Netherlands are Menaquinone-7 Supplementation to Reduce Vascular Calcification in Patients with Coronary Artery Disease: Rationale and Study Protocol (Vit K-CAC Trial), Plasma concentrations of molecular lipid species in relation to coronary plaque characteristics and cardiovascular outcome.