Eosinophilic esophagitis is a type of white blood cell (eosinophil) builds up in the lining of the tube that connects your mouth to your stomach i.e esophagus. This causes inflammation of the esophagus and damages it. Damaged esophageal tissue can lead to difficulty swallowing or cause food to get caught when one swallows. Eosinophilic esophagitis is a chronic immune system disease.
The signs and symptoms usually differ in both adults and children which includes the following: In adults:
Diagnosis and Treatment
The various tests that are performed to diagnose the disease are upper endoscopy and biopsy of esophagus, blood tests, food patch test. Steroids may decrease the buildup of eosinophils in the esophagus, reduce the inflammation associated with an allergic reaction, and allow your esophagus to heal.Acid blockers are prescribed as PPI .
There is an increasing trend in newly diagnosed cases per year worldwide. Whether this increase in incidence reflects a heightened awareness of EoE or a true increase is yet undetermined. Eosinophilic esophagitis (EoE) has been hypothesized to be an atopic inflammatory disease. The etiopathogenesis is hypothesized to be an aberrant immune response to antigenic stimulation.