Epidermolysis bullosa (EB) is a group of inherited bullous disorders characterized by blister formation in response to mechanical trauma. Recent discoveries of the molecular basis of epidermolysis bullosa have resulted in the development of new diagnostic tools, including prenatal and preimplantation testing.
Epidermolysis bullosa is classified into 3 major categories, including:
The symptoms of the disease mainly includes:
Diagnosis and Treatment
The diagnosis is done by performing a biopsy and physical examination. Routine histologic analysis is useful only for excluding other causes of blistering.The evaluation of Gene therapy for non-lethal junctional epidermolysis bullosa has been performed and shown to be efficacious in a small trial of one patient. In gene therapy, the goal is to deliver genes targeted to restore normal protein production. anemia using CBC count with iron studies in patients with severe epidermolysis bullosa, especially recessively inherited epidermolysis bullosa. There is no proper cure for this disease.