Hepatitis C virus (HCV) causes both acute and chronic infection. Acute HCV infection is usually asymptomatic, and is only very rarely associated with life-threatening disease.. The incubation period for hepatitis C is 2 weeks to 6 months. Following initial infection, approximately 80% of people do not exhibit any symptoms. Those who are acutely symptomatic may exhibit fever, fatigue, decreased appetite, grey-coloured faeces, joint pain and jaundice (yellowing of skin and the whites of the eyes).
Hepatitis C does not always require treatment as the immune response in some people will clear the infection, and some people with chronic infection do not develop liver damage. Each of the hepatitis viruses causes similar liver damage. The inflammatory process is activated throughout the whole liver, and hepatocytes are destroyed by cytotoxic cytokines and natural killer cells, both parts of the inflammatory process. Cellular necrosis takes place. If inflammation affects the periportal areas, cholestasis, or the interruption of the flow of bile takes place.
Statistics: In Netherlands the total population is 15,829,000 out of which 15,829 are Residents with Hepatitis C Infections and the Percent of Population Infected with Hepatitis C is 0.1%