Paragonimiasis is a disease caused by a parasite, also known as a fluke, which commonly infects the lungs and other body sites of humans and other mammals. The parasites most commonly associated with paragonimiasis are Paragonimus westermani and Paragonimus kellicotti although there are other Paragonimus species that can also cause disease in humans.
In approximately 20% of countries around the globe, including predominantly small islands or city-states, where Paragonimus sp. infections cannot develop for the lack of potential reservoirs, case numbers are very low, as infections of humans only accidentally occur upon the importation of Paragonimus -infected meat from abroad, the yearly total number of clinical Paragonimus was estimated to be 10,000 cases, with a death rate of 0.2%. There is a prescription drug available called praziquantel that is effective for treatment of this infection in the lungs. The usual treatment course is two days. Another prescription drug, bithionol, is also effective. Further research is being conducted to determine the drugs for the Paragonimus and how long it can affect humans.