Transposition of the great arteries (TGA) is the most common cyanotic congenital heart lesion that presents in neonates. The hallmark of transposition of the great arteries is ventriculoarterial discordance, in which the aorta arises from the morphologic right ventricle and the pulmonary artery arises from the morphologic left ventricle.
Consult with a pediatric cardiologist and a pediatric cardiothoracic surgeon. Transfer may be required for specialized diagnostic, therapeutic, and surgical interventions. Transposition of the great arteries (TGA) has no specific or recommended drug therapies. Newborn infants with transposition of the great arteries may derive some initial benefit from alprostadil (ie, prostaglandin E1) therapy. CHDs affect nearly 74,991 âbirths per year in the Netherlands. Further research is being conducted to determine Glucocorticoid therapy for hypotension in the cardiac intensive care unit