Trigeminal neuralgia (TN), also called tic douloureux, is a condition that is characterized by intermittent, shooting pain in the face.Trigeminal neuralgia affects the trigeminal nerve, one of the largest nerves in the head. The trigeminal nerve sends impulses of touch, pain, pressure, and temperature to the brain from the face, jaw, gums, forehead, and around the eyes. Although there is general agreement that none of the many existing theories fully explain all known characteristics of TGN pain the bulk of current evidence points to the trigeminal nerve rather than the CNS as the site of generation of TGN pain. More specifically, the existing evidence suggests that a slowly evolving process, whether a compression exerted on the nerve by a blood vessel or tumour or alteration of neural functions by an MS plaque at the level of the dorsal root entry zone, leads to increased excitability in some of the trigeminal afferents and subsequently to typical TGN. Patients may find immediate and satisfying relief with one medication, typically carbamazepine. However, because this disorder may remit spontaneously after 6-12 months, patients may elect to discontinue their medication in the first year following the diagnosis. Most must restart medication in the future. Furthermore, over the years, they may require a second or third drug to control breakthrough episodes and finally may need surgical intervention. Netherlands people around 319,854 among the total population are suffering from this disease that is 2.78% of the population effected.