alexa New Concept about Perioperative Asymptomatic or Symptomatic Deep Vein Thrombosis Prophylaxis in Coronary Artery Bypass Graft | Open Access Journals
ISSN: 2155-9880
Journal of Clinical & Experimental Cardiology
Like us on:
Make the best use of Scientific Research and information from our 700+ peer reviewed, Open Access Journals that operates with the help of 50,000+ Editorial Board Members and esteemed reviewers and 1000+ Scientific associations in Medical, Clinical, Pharmaceutical, Engineering, Technology and Management Fields.
Meet Inspiring Speakers and Experts at our 3000+ Global Conferenceseries Events with over 600+ Conferences, 1200+ Symposiums and 1200+ Workshops on
Medical, Pharma, Engineering, Science, Technology and Business

New Concept about Perioperative Asymptomatic or Symptomatic Deep Vein Thrombosis Prophylaxis in Coronary Artery Bypass Graft

Seyed Mohammad Yousof Mostafavi Pour Manshadi*
General Practitioner, Department of Medicine, Ali be Abitaleb Medical College, Islamic Azad University, Yazd, Iran
Corresponding Author : Seyed Mohammad Yousof Mostafavi Pour Manshadi
General Practitioner, Department of Medicine
Ali ben Abitaleb Medical College
Islamic Azad University, No 159
7th Boostan St., Pasdaran Ave. Yazd, Iran
Tel: +989133538922
E-mail: [email protected]
Received September 25, 2013; Accepted September 27, 2013; Published September 30, 2013
Citation: Mostafavi Pour Manshadi SMY (2013) New Concept about Perioperative Asymptomatic or Symptomatic Deep Vein Thrombosis Prophylaxis in Coronary Artery Bypass Graft. J Clin Exp Cardiolog 4:e131. doi:10.4172/2155-9880.1000e131
Copyright: © 2013 Mostafavi Pour Manshadi SMY. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Related article at
DownloadPubmed DownloadScholar Google

Visit for more related articles at Journal of Clinical & Experimental Cardiology

Asymptomatic deep vein thrombosis (DVT) is a common complication that occurs around of coronary artery bypass graft (CABG). It is common cause of morbidity and mortality in this process [1-4].
DVT is seen in 70-80% of patients underwent coronary artery bypass graft. The incidence of DVT is decreased with pharmacologic prophylaxis [1-4]. However, there is no unique and acceptable consensus exists.
The common prophylaxis for this purpose is administering of Low Molecular Weight Heparin (LMWH) and unfractionated heparin (UFH) [5-9]. Heparin can affect on coagulation factors and fibrinolytic proteins and restrains them. It can not affect on platelet aggregation in primary hemostasis phase. Aspirin can affect on platelet aggregation and inhibit it [5-9].
Preventing from asymptomatic DVT with heparin alone was reported 60 % to 70% and with aspirin alone was reported 40% to 50% [10,11].
Administration of heparin and aspirin together can be useful to reduce asymptomatic DVT after CABG [12].
Without using prophylactic anticoagulation, the incidence of Venous Thrombo Embolism (VTE) is high after open heart surgery but with using it the incidence of VTE is lower significantly [12-14], however administration of anticoagulants may increase bleeding but it is not significantly.
Low Molecular Weight Heparin is the best choice for DVT prophylaxis after CABG especially in patients with advanced risk factors [15].
Prevention of VTE with antiplatelet agent or anticoagulation drugs was reported in previous studies [16,17]. In Addition, administering of anti platelet and anticoagulation drug together to decrease the rate of DVT is more effective rather than antiplatelet drug or anticoagulation drug alone [15-17]. For instance, administration of heparin and aspirin together is more effective than heparin or aspirin alone to prevent from DVT [12].
Administration of anticoagulation drug and antiplatelet drug, for example aspirin and heparin, does not increase the surgical bleeding significantly [12]. However, some previous studies found that surgical bleeding increased with using of anticoagulation drug and antiplatelet agent together or with the use of them alone [18].
It sounds that administration of anticoagulation drug and antiplatelet agent together is more useful and efficient than administration of one of them alone. Also it does not increase surgical bleeding significantly. Further studies are necessary to prove administration of anticoagulation drug and antiplatelet agent together for prophylaxis of DVT in CABG.
The present editorial focuses on importance and necessity of administration of anticoagulation drug and antiplatelet drug together as prophylaxis to prevent from DVT in CABG. It is important to prevent DVT (symptomatic and asymptomatic) in CABG because of its serious complications.
References


















Select your language of interest to view the total content in your interested language
Post your comment

Share This Article

Relevant Topics

Recommended Conferences

Article Usage

  • Total views: 12107
  • [From(publication date):
    October-2013 - Aug 23, 2017]
  • Breakdown by view type
  • HTML page views : 8317
  • PDF downloads :3790
 

Post your comment

captcha   Reload  Can't read the image? click here to refresh

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords