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Hypoplastic Left Heart Syndrome

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  • Hypoplastic left heart syndrome

    Hypoplastic left heart syndrome is a complex and rare heart defect present at birth (congenital). In hypoplastic left heart syndrome, the left side of the heart is critically underdeveloped. If your baby is born with hypoplastic left heart syndrome, the left side of the heart can't effectively pump blood to the body, so the right side of the heart must pump blood to the lungs and to the rest of the body.There is no known cause in the majority of HLHS cases.There is likely a genetic component, as HLHS has been shown to be heritable and associated with specific gene mutations. 

  • Hypoplastic left heart syndrome

    Hypoplastic left heart syndrome is treated through several surgical procedures or a heart transplant. Your doctor will discuss with you the treatment options for your child. If the diagnosis has been made before the baby is born, doctors usually recommend delivery at a hospital with a cardiac surgery center. Medication to prevent closure of the connection (ductus arteriosus) between the right and left sides, followed by either surgery or a heart transplant, is necessary to treat hypoplastic left heart syndrome. 

  • Hypoplastic left heart syndrome

    Researchers actively study new treatments and surgeries for children who have hypoplastic left heart syndrome and other congenital heart diseases. Ongoing research includes studies in imaging and outcomes, human genetics and regenerative medicine strategies. Mayo doctors are also assembling a biorepository of patient and family histories, heart images, tissue and cell samples, and genomic information of people with hypoplastic left heart syndrome and their family members to further study the condition.

  • Hypoplastic left heart syndrome

    This issue of the Annals of Pediatric Cardiology contains an article entitled-“Norwood Procedure In An Emerging Economy-Initial Experience In A Single Centre.”The authors have retrospectively analyzed and presented their experience with performing the Norwood procedure in seven patients with hypoplastic left heart syndrome (HLHS) (three patients) and other single ventricle situations with uncorrectable left ventricular outflow obstruction (four patients), with five survivors. Between 1998 and 2007, the LOS for stage 1 palliation increased from 16 to 28 days and inflation-adjusted charges increased from $122,309 to $280,909, largely because of increasing survival rates (57% in 1998) and 83% in 2007.

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