Lupus is an autoimmune disease. In an autoimmune disease, the body's immune system mistakes healthy tissues and organs as foreign and potentially dangerous invaders into the body and attacks them. This results in inflammation that eventually can damage and destroy the affected tissues and organs. Corticosteroids, such as prednisone, may also be used to reduce inflammation in lupus. Anti-malarial drugs may also be used to treat the joint pain and inflammation of lupus.
Extrapolation of Prevalence Rate of Lupus is 310,216 among the estimated population of 60,270,708 for UK2 in United Kingdom. Lupus is an ongoing or chronic disease that can have a widespread effect on the body, including the skin, joints, muscles and other organs. Lupus, also called systemic lupus erythematosus, can be a mild disease or the progression of it can result in serious, even fatal complications to vital organs.
Medications commonly used to treat lupus include non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil) and aspirin. NSAIDs are very effective in treating the pain and inflammation of mild lupus. However, long-term use of NSAIDs can cause serious, even life threatening, side effects and adverse events. These include bleeding gastrointestinal ulcers and possible heart problems and cardiovascular events.
NIAMS researchers have found a gene linked to a higher risk of lupus kidney disease in African Americans. Researchers are looking into the role of hormones and other male-female differences. One NIAMS project is testing a new drug that scientists hope will have milder side effects than standard treatments. Another study is testing a combination of two medicines. One is a standard drug and the other is a new drug. Scientists hope that the combination will be more effective and cause fewer side effects.