Stuttering is an interruption of the normal flow of speech, which takes on many different patterns. Commonly, it involves either saying a string of repeated sounds or making abnormal pauses during speech. In early childhood, stuttering is sometimes part of normal speech development. In fact, about 5% of all young children go through a brief period of stuttering when they are learning to talk. Stuttering typically is first noticed between the ages of 2 and 5. It usually goes away on its own within a matter of months. In a small number of children (around 1%), stuttering continues and may get worse. Boys are more likely to stutter than girls.
In addition, normal problems with fluency tend to come and go, or happen only at certain times (such as when a child is tired or excited), but true stuttering is present most of the time. Once a child begins to stutter, he or she may feel embarrassed, self-conscious or anxious when asked to speak. The child may find it hard to socialize with friends and also may intentionally avoid situations where talking is expected, such as telephone calls, classroom discussions and school plays. Somewhat unexpectedly, many children who stutter have no problem when they sing. According to some experts, this is because speaking and singing often come from opposite sides of the brain, especially in right-handed people.
Antibiotic use in Europe, expressed in defined daily dose (DDD) per 1000 inhabitants, ranges from 10.0 in the Russian Federation, 14.6 in Sweden to 45.2 in Greece, according to 2008 data from the European Surveillance of Antimicrobial Consumption (ESAC) project. The statistics depend on the strength of monitoring systems. In the European Union (EU), Norway and Iceland, 5–12% of hospital patients acquire an infection during their stay. Each year, an estimated 400 000 present with a resistant strain, of whom 25 000 die, on average. In addition to causing deaths and increased suffering, AMR has huge economic implications.