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Pathophysiology
Waldenstrom macroglobulinemia (WM).could be a chronic, indolent, lymphoproliferative disorder. It Is characterised by the presence of a high level of a macroglobulin (immunoglobulin M [IgM]), elevated human body, and also the presence of a lymphoplasmacytic infiltrate within the bone marrow.
Statistics
Deaths, emigrations, and incident cases of LHMs in these cohorts were identified by linkage to the Death Registry at Statistics Norway and to the Cancer Registry of Norway. The two registries are population based, covering the entire Norwegian population. A unique 11-digit identification number assigned to all individuals living in Norway after 1960 simplified the linkages.
Treatment
Ought to be supported individual patient and illness characteristics (age, comorbidities,would like for fast illness management, campaign for autologous transplantation, cytopenias, IgM-related complications, hyperviscosity, neuropathy). Autologous vegetative cell transplantation is also thought of in young patients with chemosensitiveillness and in freshly diagnosed patients with very-high-risk options.
Research
Eleven Norwegian hospitals participated, and patients were enrolled between February 1, 2005, and October 31, 2009. We have also included in this report 3 pilot patients treated in 2004 according to the same protocol.