alexa A Circumscribed and Persistent Erythematous Plaque on the Palm | OMICS International
ISSN: 2155-9554
Journal of Clinical & Experimental Dermatology Research

Like us on:

Make the best use of Scientific Research and information from our 700+ peer reviewed, Open Access Journals that operates with the help of 50,000+ Editorial Board Members and esteemed reviewers and 1000+ Scientific associations in Medical, Clinical, Pharmaceutical, Engineering, Technology and Management Fields.
Meet Inspiring Speakers and Experts at our 3000+ Global Conferenceseries Events with over 600+ Conferences, 1200+ Symposiums and 1200+ Workshops on
Medical, Pharma, Engineering, Science, Technology and Business

A Circumscribed and Persistent Erythematous Plaque on the Palm

Baliu-Piqué C, Alós L and Mascaró Jr. JM*

Departments of Dermatology and Pathology, Hospital Clínic de Barcelona, Universitat de Barcelona, Spain

*Corresponding Author:
José M. Mascaró Jr
Associate Professor Department of Dermatology
Hospital Clínic, Calle Villarroel 170
08036 Barcelona, Spain
Tel: +34932279867
Fax: +34932275438
E-mail: [email protected]

Received date: September 24, 2014; Accepted date: November 13, 2014; Published date: November 24, 2014

Citation: Baliu-Piqué C, Alós L, Mascaró Jr. JM (2014) A Circumscribed and Persistent Erythematous Plaque on the Palm. J Clin Exp Dermatol Res 5:247. doi: 10.4172/2155-9554.1000247

Copyright: © 2014 Baliu-Piqué C, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Visit for more related articles at Journal of Clinical & Experimental Dermatology Research

Case Report

A 66 year-old white woman had a unique cutaneous lesion localized at her right thenar eminence. It was a shiny erythematous round plaque with a clear scaling border that was slightly depressed (Figure 1A). The lesion was completely asymptomatic and had been noticed by the patient many years before. It had 1.5cm of diameter and had been stable during all these years. Dermoscopy showed a depressed erythematous area on the centre, surrounded by a thick border (Figure 1B). There is a depression of epidermis caused by a reduction in the thickness of the horny layer, with well-defined borders (H&E, original magnification ×40) (Figure 1C) and there is a slight thinning of the granular layer without noticeable morphological abnormalities on underlying keratinocytes (H&E, original magnification ×200) (Figure 1D). She refused any treatment.


Figure 1: A) Shiny erythematous round plaque with a clear scaling border. B) Dermoscopy C) Depression of epidermis D) Morphological abnormalities

Circumscribed palmar or plantar hypokeratosis (CPH) is a rare condition that is usually asymptomatic. This process was first described in 2002 by Pérez et al. [1].

CPH is an acquired disorder that is more common in women and the age at the first visit to a physician ranges from 42 to 84 years (mean age 64.6 years). In a large majority of cases there is a single lesion, consisting of a well-demarcated erythematous plaque with central depression and scaly border separating it from normal skin with characteristic histopathologic features [2]. This condition is currently considered as a localized keratinization disorder affecting areas with a thick stratum corneum. The precipitating cause is currently unknown and a definitive treatment remains to be found. The hand is the usual location, more commonly on the thenar eminence, with no preference for the right or left hand. Malignant transformation has never been reported up to date. The main differential diagnoses are Mibelli porokeratosis, Bowen disease and the base of a blister in the erosion stage. Due to the frequent lack of efficacy of treatments and the benignity of this entity, observation alone can be considered as an adequate procedure.


Select your language of interest to view the total content in your interested language
Post your comment

Share This Article

Relevant Topics

Recommended Conferences

Article Usage

  • Total views: 11775
  • [From(publication date):
    November-2014 - Jun 18, 2018]
  • Breakdown by view type
  • HTML page views : 8004
  • PDF downloads : 3771

Post your comment

captcha   Reload  Can't read the image? click here to refresh

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7