Reach Us +44-1753390542
A Fatal Infection Caused by Streptococcus Equi Zooepidemicus: An Emerging Pathogen for Humans | OMICS International
ISSN: 2165-7548
Emergency Medicine: Open Access
Make the best use of Scientific Research and information from our 700+ peer reviewed, Open Access Journals that operates with the help of 50,000+ Editorial Board Members and esteemed reviewers and 1000+ Scientific associations in Medical, Clinical, Pharmaceutical, Engineering, Technology and Management Fields.
Meet Inspiring Speakers and Experts at our 3000+ Global Conferenceseries Events with over 600+ Conferences, 1200+ Symposiums and 1200+ Workshops on
Medical, Pharma, Engineering, Science, Technology and Business

A Fatal Infection Caused by Streptococcus Equi Zooepidemicus: An Emerging Pathogen for Humans

Finazzi MG*, Eusebi G, Salemi A and Durante V

Cervesi Hospital, Cattolica, Italy

*Corresponding Author:
Finazzi MG
Internal Medicine, Cervesi Hospital
Internal Medicina Department, Beethoven
Cattolica, Rimini, Italy
Tel: +393472335467 Email: [email protected]

Received Date: February 16, 2015; Accepted Date: February 23, 2015, 2015; Published Date: March 02, 2015

Citation: Finazzi MG, Eusebi G, Salemi A and Durante V (2015) A Fatal Infection Caused by Streptococcus Equi Zooepidemicus: An Emerging Pathogen for Humans . Emerg Med (Los Angel) 5:248. doi:10.4172/2165-7548.1000248

Copyright: ©2015 Finazzi MG, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Visit for more related articles at Emergency Medicine: Open Access


To the Editor

Streptococcus equi subspecies zooepidemicus (S. zooepidemicus ) is an emerging zoonosis [1]. It is an opportunistic commensal in horses and it can rarely cause disease in humans who have contacts with animals (horses, cattle, sheep, pigs, dogs, cats) or following consumption of unpasteurized milk products [1-3]. It can cause a severe and potentially fatal disease [1,4].

We here report a case involving a 51-year old Caucasian man who was admitted to hospital on 23th December 201, because of a severe and persistent bilateral inguinal pains, irradiating to both legs, lasting from 6 hours. He reported a single febrile episode the day before, successfully treated with paracethamol. On admission, the patient was afebrile, alerted and oriented. His heart rate was 80 beats/min and the blood pressure was 120/ 70 mmHg. Blood tests were as follows: Creactive protein 25.6 ng/ml (reference <5), white blood cell count 6050 cells/ml, hemoglobin 12.6 gr/dl, platelet count 53000 cells/mmc (in line with previous values, reference 140.000-400.000), creatine phosphokinase 113.000 U/L (reference <240), mioglobin 17204 ug/L (reference <72) and aspartate transaminase 1810 U/l (reference <40). The renal function and the electrolytes were within normal range. Clinical examination was unremarkable, in particular no skin lesions were detected. A CT scan of the thorax and abdomen showed a pulmonary infiltrate in the left lung, hepatomegaly and splenomegaly (consistent with previous report), with hypertrophy of the ileo-psoas and left medius gluteus muscles, along with a subcutaneous hyper density in the left buttock. The Magnetic Resonance Imaging showed an interstitial edema of the ileo-psoas muscles, while, in the pelvis, a bilateral edema of the adipose tissue was present without any fluid level.

After blood cultures, the patient was empirically started on intravenous vancomicin (500 mg qid) plus meropenem (1 gr tid) and referred to intensive care unit because of the rapid clinical deterioration, where he died 12 hours after admission. Blood cultures yielded Lancefield group C Streptococcus equi (subspecies Zooepidemicus) 24 hours later with the antibiogram showing susceptibility to penicillin, ciprofloxacin, vancomicin and resistance to clindamycin. The patient suffered from HCV-related liver cirrhosis (Child-Pugh A) and had a history of urethelial carcinoma (currently in clinical remission) and in 2013 he was admitted to hospital for decompensated liver disease and sepsis caused by E. coli . He has been working as a horse keeper in a riding stable and he was also involved in cleanings of equine urine and feces.

In humans the disease caused by S. zooepidemicus may have a proteiform clinical presentation as it may cause pneumonia, meningitis, endocarditis, endophtalmitis, skeletal involvement with and without sepsis [4-7]. In some case, as in ours, the absence of fever, the mild increment of inflammation markers and persistent pains with severe rhabdomyolysis require a high index of suspicion. Antimicrobial treatment includes penicillin G or cephalosporins as treatment of choice for group C streptococcus infections, although gentamicin or rifampin in combination with a beta-lactam antibiotic or vancomycin may have a synergistic effect [8]. The mode of transmission to humans includes close contact (areal or skin contact?) or ingestion of unpasteurized milk or dairy products from infected animals [1-3]. Clinicians should be aware of this emerging, uncommon and potentially life threatening condition, mostly (but not limited to) involving persons with close and continuous contacts with horses.


Select your language of interest to view the total content in your interested language
Post your comment

Share This Article

Relevant Topics

Article Usage

  • Total views: 13470
  • [From(publication date):
    May-2015 - Jan 23, 2019]
  • Breakdown by view type
  • HTML page views : 9653
  • PDF downloads : 3817

Post your comment

captcha   Reload  Can't read the image? click here to refresh

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2019-20
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri and Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

ankara escort

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

pendik escort

[email protected]

1-702-714-7001Extn: 9042

© 2008- 2019 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version