|Lei Wang1, Hua-ping Pan2, Zun Wang1, Zhen-yu Cao1, Jia-jia Qian1 and Bin Xu3*|
|1Rehabilitation Therapy Department, Nanjing University of Chinese Medicine, Nanjing-210029, China|
|2Department of Rehabilitation Medicine, the Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing-211100, China|
|3National Key Laboratory of Acupuncture and Medicine of China, Nanjing University of Chinese Medicine, Nanjing-210029, China|
|Corresponding Author :||Bin Xu
National Key Laboratory of Acupuncture and Medicine of China
Nanjing University of Chinese Medicine
E-mail: [email protected]
|Received: May 27, 2015; Accepted: July 3, 2015; Published: July 10, 2015|
|Citation: Wang L, Pan H, Wang Z, Cao Z, Qian J, et al. (2015) Additive Effect of Moxibustion Therapy and Treadmill Exercise as a Treatment for Intermittent Claudication Associated with Peripheral Arterial Disease. J Clin Exp Cardiolog 6:381. doi:10.4172/2155-9880.1000381|
|Copyright: © 2015 Wang L, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.|
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Methods: 80 PAD patients were randomly assigned into a control group (CG, n=20), a moxibustion therapy group (MG, n=20), a treadmill exercise group (TG, n= 0) and a moxibustion therapy combined with treadmill exercise group (MTG, n=20) with the treatments of 18 weeks. Outcome measurements were lower limbs' transcutaneous oxygen tension (TcPO2), treadmill-walking test to determine when claudication pain begins and how long it takes to reach the maximum claudication pain, 6-minute walking test (6MWT) and walking impairment questionnaire (WIQ).
Results: MG, TG and MTG treatment groups showed a significantly better curative effect (p<0.05) in all of the outcome measurements. Compared to MG, the TG and MTG showed significantly more improvement in the treadmill exercise test as well as in the 6MWT and WIQ (p<0.05); compared to TG, MTG was better in treadmill walking time to reach maximum claudication pain, 6MWT and the stair-climbing capability in WIQ (p<0.05).
Conclusion: Moxibustion therapy in combination with treadmill exercise can improve the lower limber microcirculation, relieve symptoms of intermittent claudication, and improve quality of life of PAD patients. Moxibustion combined with treadmill exercise shows further improvement in low limber exercise capacity.
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