Agenesis of Celiac Axis A Rare Clinical Entity
Received Date: Jan 26, 2016 / Accepted Date: Feb 10, 2016 / Published Date: Feb 15, 2016
Agenesis of celiac axis (AGCA) is one of the rare anomalies of abdominal aorta. Very few cases have been reported in the medical literature in the past mainly on angiographic studies performed for various indications. With the advent of multidetector computed tomography (MDCT), it is now possible to detect anomalies of abdominal aorta on routine abdominal MDCT scans performed for indications other than angiography. Detection of these anomalies has assumed significant importance due to increasing number of interventional procedures; minimally-invasive and transplantation surgeries and also in understanding the morbidity and mortality related to diseases involving the anomalous arteries. Hence, we are presenting a rare case of agenetic celiac axis that was diagnosed incidentally on routine MDCT abdominal examination.
Keywords: Agenesis; Celiac axis; MDCT
AGCA is a rare anomaly of abdominal aorta with an estimated incidence of 0.1 to 2.5% according to one morphometric study of celiac trunk performed on adult human Caucasian cadavers . According to one study, only 31 cases have been reported in the world medical literature, out of which only one-third cases have been reported on imaging studies mainly on angiography with rest of them reported on anatomical dissection [2,3]. With the advent of variety of interventional, transplantation and minimally-invasive surgical procedures, knowledge of these anatomical variations have become very significant to avoid inadvertent complications. Advent of MDCT has made detection of these abdominal aortic anomalies possible on routine as well as angiographic scans. Prior knowledge of these variations also aid in early institution of therapy/interventional procedure (vascular grafts) in suspected occlusion of these anomalous arteries.
A 26-years old female with history of vague abdominal pain came for contrast-enhanced MDCT scan of whole abdomen as previous hematological, biochemical, radiographic and ultrasonographic investigations were unremarkable.
The abdominal scan revealed horse-shoe kidney without obvious calculus or hydronephrosis. No evidence of any other obvious visceral pathology was noted to explain the cause of vague abdominal pain. However, careful examination of abdominal aorta revealed absence of celiac axis as an incidental finding. Common hepatic, splenic and left gastric arteries had anomalous origin from a vascular trunk that was arising from the proximal part of superior mesenteric artery. These findings established the diagnosis of a genetic celiac axis.
Celiac axis or trunk is the first branch of abdominal aorta arising from the ventral aspect at the level of D12 vertebral body. The classical trifurcation of celiac artery in to common hepatic, splenic and left gastric arteries is known as Tripus Halleri. Superior mesenteric artery is the second ventral branch arising at the level of L1 vertebral body.
• Several variations of celiac artery are known to occur including:
• Absence of one of its branches (bifurcation or incomplete celiac trunk);
• Additional branches;
• Common origin with superior mesenteric artery (celiacomesenteric trunk);
• Common origin with superior and inferior mesenteric arteries (celiac-bimesenteric trunk) and
Agenesis of celiac artery (AGCA) is a rare entity [1,2]. Very few cases have been described in medical literature in the past that were detected on imaging studies primarily on angiography [3-6]. With the advent of multidetector CT, incidental detection of these congenital anomalies along with other abnormalities is now possible even on routine abdominal examinations.
AGCA is diagnosed by lack of major vascular trunk arising from abdominal aorta at the level of D12 vertebral body. It is also associated with other vascular anomalies, for example common hepatic, splenic and left gastric arteries may arise separately from aorta [7,8] or from a vascular trunk arising from superior mesenteric artery at the level of L1 vertebral body as seen in our case as well as in few cases described previously in medical literature . In addition, horse-shoe kidney was also noted in our case that has not been described previously in medical literature (Figure 1).
With the advent of various interventional procedures (for example: arterial embolisation, transarterial chemoembolisation, arterial grafts); minimally-invasive surgical procedures (for example: laparoscopic and robotic procedures) and organ transplantation, knowledge of these anatomic variations have become exceedingly important to avoid various complications. Also prior knowledge of these variations may aid in early institution of treatment when occlusions of these anomalous arteries is suspected as a cause of ischemia to abdominal viscera.
The above-described variations can be detected noninvasively by contrast-enhanced MDCT abdominal angiography as well as routine contrast-enhanced MDCT abdominal scans performed for other indications (Figure 2).
Variations in branching pattern of abdominal aorta can be easily detected on routine contrast-enhanced MDCT abdominal scans. Knowledge of these variations especially the rare anomaly of celiac axis agenesis with associated findings not only help in determining the extent of abnormality with superior mesenteric artery disease but this knowledge may also be helpful while performing various transplantation, laparoscopic, interventional and arterial graft procedures.
- Venieratos D, Panagouli E, Lolis E, Tsaraklis A, Skandalakis P (2013) A morphometric study of the celiac trunk and review of the literature. Clin Anat 26: 741–750.
- Yi SQ, Terayama H, Naito M, Hirai S, Alimujang S, et al. (2008) Absence of celiac trunk: case report and review of the literature. Clin Anat 21: 283-286.
- Iacob N, Sas I, Joseph SC, Ples H, Miclaus GD, et al. (2014) Anomalous pattern of origin of the left gastric, splenic, and common hepatic arteries arising independently from the abdominal aorta. Rom J Morphol Embryol 55: 1499-1453.
- Matusz P, Miclaus GD, Ples H, Tubbs RS, Loukas M (2012) Absence of the celiac trunk: case report using MDCT angiography. Surg Radiol Anat 34: 959-963.
- Basar R, Onderogul S, Cumbur T, Yuksel M, Olcer T (1995) Agenesis of celiac Trunk – an angiographic case. Kaibogaku Zasshi70: 180-182.
- Mersten A (1990) Angiographic diagnosis of agenesis of celiac trunk. Cesk Radiol 44: 32-36.
- Fahmy D, Sadek H (2015) A case of absent celiac trunk: case report and review of literature. The Egyptian Journal of Radiology and Nuclear Medicine 46: 1021-1024.
- Douard R, Chevallier JM, Delmas V, Cugnenc PH (2006) Clinical interest of digestive arterial trunk anastomosis. Surg Radiol Anat 28: 219–227.
Citation: Rastogi R, Meena GL, Gupta Y, Majid A, Joon P (2016) Agenesis of Celiac Axis – A Rare Clinical Entity . J Colitis Diverticulitis 1: 103.
Copyright: ©2015 Rastogi R, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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