alexa Beta-lactomics|genomics|proteomics|metabolomics|transcriptomics
ISSN: 0974-276X
Journal of Proteomics & Bioinformatics
Like us on:
Make the best use of Scientific Research and information from our 700+ peer reviewed, Open Access Journals that operates with the help of 50,000+ Editorial Board Members and esteemed reviewers and 1000+ Scientific associations in Medical, Clinical, Pharmaceutical, Engineering, Technology and Management Fields.
Meet Inspiring Speakers and Experts at our 3000+ Global Conferenceseries Events with over 600+ Conferences, 1200+ Symposiums and 1200+ Workshops on
Medical, Pharma, Engineering, Science, Technology and Business

Beta-lactomics: A New Term Coined in “OMICS”

Asad U Khan*

Medical Microbiology and Molecular Biology laboratory Interdisciplinary Biotechnology Unit, A.M.U., Aligarh, India

*Corresponding Author:
Asad U Khan
Medical Microbiology and Molecular Biology laboratory
Interdisciplinary Biotechnology Unit
A.M.U., Aligarh-202002, India
E-mail: asad.k@rediffmail.com

Received Date: October 25, 2014; Accepted Date: October 28, 2014; Published Date: October 29, 2014

Citation: Khan AU (2014) Beta-lactomics: A New Term Coined in “OMICS”. J Proteomics Bioinform 7:e27. doi: 10.4172/jpb.10000e27

Copyright: © 2014 Khan AU. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Visit for more related articles at Journal of Proteomics & Bioinformatics

In English language OMICS informally refers to a field of study in biology ending in -omics, such as genomics, proteomics, metabolomics, transcriptomics etc. The related suffix -ome is used to address the objects of study of these fields such as the genome, proteome, metabolome and transcriptome respectively. The Omics aims at the complete characterization and quantification of pools of biological molecules and their structural and functional insight of an organism. The idea of beta-lactomics came after the worldwide spread of different groups of beta-lactamases and their variants among different strains of bacteria [1,2]. Beta-lacatmases are enzymes coded by specific gene and produced in bacteria to hydrolyze antibiotics and hence cause drug resistance against antibiotics a major health problem. A total of about hundreds of variants of each groups of beta-lactamases have been identified and documented in form of manuscripts and databases in the public domain [3-5]. The structural and function diversity of these enzymes are remarkable as evident from the fact that a single mutation may changed its activity towards antibiotic hydrolysis. Some of the structures of these beta-lactamases have been explored using X-ray crystallography and other biophysical techniques but still there are many left in the pool which has not yet been solved for their structural and functional understanding. It is important to understand the structure of these enzymes to map the newly designed lead molecules as future drug candidate [6]. Designing drug is an emerging area as it has become a need of an hour since almost all antibiotics are getting ineffective after the discovery of “Superbug” and spread of NDM-1 enzyme [7,8]. Moreover, natural products are also screened against bacterial infections caused by multiple drug resistant starins. We have proposed several novel approches to inhibit the action of these enzymes in bacteria [9,10]. The study is in progress on these aspects of betalactamases besides their epidemiology and surveillance studies in order to control hospital infection. Hence, a new name as beta-lactomics may be given to this field of beta-lactamases and their emerging variants in bacteria causing multiple drug resistance.

Hence, I am proposing a new term (Beta-lactomics) for this field. It has become a need in the current scenario to understand the whole lot of proteins of this kind circulating in the environment and hospital setting. The control measures of infection can be attained by designing new empirical treatment based on the information gathered through this field. Moreover, databases of these enzymes and proteins are also required to provide functional and structural information for the researchers working in this area.

References

Select your language of interest to view the total content in your interested language
Post your comment

Share This Article

Relevant Topics

Article Usage

  • Total views: 11622
  • [From(publication date):
    October-2014 - Nov 25, 2017]
  • Breakdown by view type
  • HTML page views : 7841
  • PDF downloads : 3781
 

Post your comment

captcha   Reload  Can't read the image? click here to refresh

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

agriaquaculture@omicsonline.com

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

biochemjournals@omicsonline.com

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

business@omicsonline.com

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

chemistryjournals@omicsonline.com

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

clinicaljournals@omicsonline.com

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

engineeringjournals@omicsonline.com

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

nutritionjournals@omicsonline.com

1-702-714-7001Extn: 9042

General Science

Andrea Jason

generalscience@omicsonline.com

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

geneticsmolbio@omicsonline.com

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

immunomicrobiol@omicsonline.com

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

materialsci@omicsonline.com

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

nursinghealthcare@omicsonline.com

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

medicaljournals@omicsonline.com

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

neuropsychology@omicsonline.com

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

pharmajournals@omicsonline.com

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

social_politicalsci@omicsonline.com

1-702-714-7001Extn: 9042

 
© 2008- 2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords